LOCUS       MGYG000003393_10       13338 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  MGYG000003393_10.
ACCESSION   MGYG000003393_10
VERSION     MGYG000003393_10
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.0.0
            Run date     :: 2023-06-28 20:46:21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 275302
            Orig. end    :: 288640
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13338
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8338]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8338
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..13338
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13338
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(49..1278)
                     /gene_functions="other (smcogs) SMCOG1054:hypothetical
                     protein (Score: 90.4; E-value: 2.7e-27)"
                     /gene_kind="other"
                     /locus_tag="ctg10_269"
                     /transl_table=11
                     /translation="MQLPASANTVVSASSRYDARVLCIEVPFVSPETDNRAVMALFAEH
                     KDLIGLPVVENGKPFGMINRHIFLSQMARPFFPELYDRKSCIAFMDKFPLVIDVENTLE
                     SVAQQVVANGDKSVADGFILTENGHYIGIGLGIDLIRRVSDLQARQHQQILQSIDYARV
                     IQDAMLDRSNQLIASLLDDWCLYWQPRDGVGGDYYAFHRHDNGWLAVIADCTGHGIPGA
                     FMTVILQSALENALREADLQAPASILHALNHHIKQTLGQLNASQQTSLSNDGCDAIVMS
                     VDTGLHQLRWASARTQAFMLSNISNEIISLSQDRVGVGYTDTPEDYHWPEQSLAFNPGD
                     MLFVLTDGVTDQPGGERNIMFGNKRIQSLLMRYQHLPMAELSLAFQQDYLSWQGNQARR
                     DDVTWFGFRY"
     CDS             complement(1505..1987)
                     /locus_tag="ctg10_270"
                     /transl_table=11
                     /translation="MPTQDIRCLKIMYVSSYSFLLLFSLLGYPGNNSLLRYLISSHTAK
                     LRVVQGNDEMRLCAIPAHMLSASHSENADHRNRKPEHYDRVNQPYPNNITALKPSNAKT
                     PAEARVSNLWCPNPESNQGHGDFQSPALPTELFGQRGALNLKQAPASNAFHKNEIN"
     CDS             3852..3974
                     /locus_tag="ctg10_271"
                     /transl_table=11
                     /translation="MKNLHSKINLLDSERDTDIQTVERRERSVKRAERNLVQAE"
     CDS             5001..5855
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 240.7;
                     E-value: 3.1e-73)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_272"
                     /sec_met_domain="phosphonates (E-value: 1.5e-101, bitscore:
                     334.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 4.3e-70, bitscore:
                     230.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKKLIAEKGTLIFIEAHNPLSALIASKAEQTNSEGRIVKFDGIW
                     SSSLTDSASRGIPDNETLALSSRLENIADIRNVTDMPIIMDADTGGKPEHFSYYVKRMI
                     NNGVNGVIIEDKTGLKKNSLFGTEVEQTLADINDFSEKIKRGKSAVYIDDFMIIARLES
                     LIAGFDVEHALERADAYVEAGADGIMIHSCKKTPDEVFLFSTKFRKKYPSVPLICVPTT
                     YSATSNRELSEAGFNVIIYANHMLRAAYKAMENVSKEILRYGRTAEIEKSCMSVKEIIS
                     LIP"
     CDS             5867..7195
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083:oxidoreductase (Score: 46; E-value: 7.6e-14)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_273"
                     /transl_table=11
                     /translation="MKKKEMIIGAYISYGTGHHPASWRESGVNAAAALDIDTYANLARV
                     CEKGLADLLFLADTPSVFQDNMDGYGSRVSVLEPLSLLSYLASQTQNIGLVATASTTYK
                     HPYNIAREFASLDYISKGRAGWNLVTSSKSDAAKNFGLAAHPEHSKRYDMAWEAWQVIS
                     GLWDSWEDNALVRNKTSGQFFVKDKYREINFEGEYFNVKGPLNIARPPQGYPVIVQAGS
                     SEEGKELAAKTADIVFTAQNNIEDAKKFYDDLKGRMEKYGRSKSELLILPGLSFYIASD
                     ESKARKKLNDLNALIPQSFGLSMLSDLLGGVDLKNNDPEGPLPDLPKSNGNQSRQKIII
                     DLARKEKLSIKQLYEKIIISRGHYTFTGSYQDLADEMIKWVENEACDGFNIMPPLMPES
                     LINLFDHVIPLIQARGWYKKSYSTGTLREKLGLKRPTNKLFNQ"
     CDS             7217..8338
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 338.9;
                     E-value: 8.8e-103)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_274"
                     /sec_met_domain="HMGL-like (E-value: 1.6e-75, bitscore:
                     248.9, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNKNLILEDTTLRDGEQAPGVAFTPEQKVEIFYLLANMGVKWIE
                     AGIPAMKGDEVKALSEMLERKNEINIIAWNRGVLEDIEYSISLGFKAVHIGLPTSAIHL
                     EKSVKKDKSWLVKTASDLVKFAKDKGMFVSISAEDIGRTDIGFLQEYAQVVAEAGADRL
                     RLSDTIGILSPAQYKEKVSLLNKNVNIDLQCHCHNDFGFAVANTLAGIEAGARYFHVCV
                     NGIGERAGMPDLAQVAMALHFFHGVDLGLDLTKLIALSETVARYSHQKISPWQPIVGDN
                     VFAHESGIHANGMLKDSSTFEPFDPATVGGERRLVVGKHSGRAIIKHFLEESGVKAADD
                     KALDRCLERVRSHAVRHPGGIPPHVLVDLYTAG"
     CDS             8345..9583
                     /locus_tag="ctg10_275"
                     /transl_table=11
                     /translation="MKSNQPIVNQIIASHSGRGQVSAGELITVDVDYVYVQDGNSPTVA
                     KLFQDYHLSEVLKPDKIGFFFDHSVLVPDKTMAKRVNEAMEFAKKLGINIYSRGEGISH
                     VIALESKIFKPGNIVLGADSHTCTGGAVQSLALGMGASDILVAMLTGQTWLKVPQTVHL
                     CIKGKTGKDVRAKDVMLALLNKYGQTPFLYKSIEVSGEWAEELTLDEAASFASMAVELG
                     AKCIFMPDGQGRPEGLLKADASVADSVINFSVSELMPHIAPPHSPLYAKPANDFEGLKF
                     DYIFIGSCTNSRLEDIKEVAEIVAGKTIHPDIHCLLTPGSKSVYLKALQAGYIDTLIRS
                     GIIVTPPGCGACVGTQGTIPADGEKVLSTMNRNFKGRMGNAEADIFLCSPRTAAMVALN
                     GTVPHFEGESAYE"
     CDS             9576..10109
                     /locus_tag="ctg10_276"
                     /transl_table=11
                     /translation="MSKTAENYRVRRVEGNISTDDIIPARYKHMYTEPAQLAPHLFESR
                     FPGFRETLSINDVLVCDQIFGIGSSREQAVTTLLACGVKYVFSPSFGRIFFRNSWNLGL
                     HAIEVDTSELADLSEIKIELTGGVIYTENNQINFFPPSSQMTAIVSAGGIIPYTINKIM
                     EKKGDILRGYSNEK"
     CDS             10099..10866
                     /locus_tag="ctg10_277"
                     /transl_table=11
                     /translation="MKSEKFDGLADNYDKYRPRYPAILFKEIHDWMQPSAKNIYDIGAG
                     TGIAIEGMTRVTGKHYDFTAIDISEDMIKKGREKLPGTTWVKGKAEDILSDKSRIDVIM
                     AAQSFQWMDRAKTLEVSIKSLNKGGVFAVLQNNRDYRNNEMLNKYEGLLEKFSPGYSRH
                     YRDYDYENEITNVFKLPIANFKKVVTGWTMEMISEDFFGFISSSTQVQRAIENDRNGFW
                     KEIEILIDEHSVGGKISIDYISELFIAKKRDDS"
     CDS             10856..11332
                     /locus_tag="ctg10_278"
                     /transl_table=11
                     /translation="MIHSMTIQDISIEQASYEDAKLLRKALEKVYEPYTLNFSPTALQF
                     TENIIAQESSKWLVAKYKSDIVGAVRYELYDIYLDFHFLCVTPPFRKMGVGNELFHKLK
                     KIAYEKRKDFMKIVLRDSLSYNRRYFESKGFYFYHKYQTNMHSVFILKLNGEKP"
     CDS             11329..12432
                     /locus_tag="ctg10_279"
                     /transl_table=11
                     /translation="MNKKALVIGLKSNMERVIKGLNEIEFIIIDRGTLDNESIDYIINL
                     SDDLMHKKSFSYVIASSEDFIALAGLLRNRYSLYGEKYYKSTIATNKFLMRNFCSGFLS
                     CPKFWLSGEIINSENLLLSSQKDYIVKPLTGSSAKHVETVTQEDLNQYLNENNKLMLIE
                     EKVLMRDEYHLDCIIKDGNILFSTLSIYDRPILEAKSKNRASINLPDGTRLHEDALILA
                     TNLQSHFEMTNGVFHIEMYHTQDGFILGEFGIRPPGAGVTDMYYMYRGVDFWEAFIYSQ
                     IDKEFILPLNHKSDKYCAAIGICSSFPVDDIRSTSKVSVDKYVNLRENAAKPAVPSSTS
                     FNHMIYVSSSSLEEIRNFLHDISDRQE"
ORIGIN
        1 aagggcagac cccgtagtga ctcgtttttc attttcttcc cggtgcagtc aatagcgaaa
       61 gccaaaccag gtgacgtcat cgcgtcgcgc ctgattacct tgccagctta aatagtcttg
      121 ctgaaacgcc agcgataact ccgccatagg caaatgctga tagcgcatca gcagagactg
      181 aatacgctta ttgccaaaca tgatattccg ttcgccaccc ggttgatcgg tgacgccatc
      241 cgtgaggaca aacagcatgt cgcccggatt aaacgccagg ctctgttcag gccagtgata
      301 gtcttccggc gtatcggtat agccgacgcc gacgcgatcc tgactgagcg agataatttc
      361 attgctgatg ttgctgagca taaatgcctg ggttcgggcg ctggcccagc gcagctgatg
      421 cagtccggta tcaactgaca tcacgatggc atcgcagcca tcgttagaga gtgaggtttg
      481 ctgggaggcg ttcagctggc ccagggtttg tttaatatgg tgattaaggg catgcaggat
      541 gctggcaggt gcctgcagat cggcctcgcg cagcgcgttt tccagcgcag actgcaaaat
      601 caccgtcata aaagcgcctg gaattccgtg gcccgtacag tcggcgatga ccgccagcca
      661 gccattgtca tggcggtgaa aagcgtagta atcgccgccc acgccgtctc ggggctgcca
      721 gtacaaacac cagtcgtcga gcagggaggc aatcagctgg ttggaacgat ccagcatcgc
      781 gtcctgaatg actcgcgcgt aatcaatgct ttgtaaaatt tgctgatgct ggcgcgcctg
      841 caaatcggag acgcggcgaa tcagatcgat ccccaagcca atgccgatat agtgcccgtt
      901 ctccgtcagg ataaacccat cggcgacgga cttatccccg ttggccacga cctgctgcgc
      961 aacgctttcc agcgtatttt ccacgtcaat caccagcggg aacttatcca taaaggcaat
     1021 gcagctcttg cggtcataga gttcgggaaa gaaagggcgc gccatctgcg acaaaaagat
     1081 gtggcggttg atcatgccga acggcttgcc gttttccacc acgggcaacc cgatcagatc
     1141 tttgtgttcg gcaaagagtg ccatgacggc acggttatct gtctccggac tgacgaaagg
     1201 gacctcaatg cataacaccc gcgcgtcata acggcttgag gcggaaacca cagtattcgc
     1261 agaggcgggt aactgcatga tgcggctctt gattgtccag gaataatctt agagtaatga
     1321 gcgcagatga cggatttatg gcaaaaaaac ggttggtaaa aagagggccg ataaatcgca
     1381 gttaaagcaa aattgcagcg aaaaatagcc tgccagaggg cgttctgcag cgcgaaaatc
     1441 cggcggttga ttgggcggat tgttaaattt tcgcccgttc cccttcctgt tgatggaaaa
     1501 cccgtcagtt gatttcattt ttgtgaaaag cgtttgacgc tggggcctgc ttaaggttta
     1561 atgcgccccg ttgcccgaat agctcagtcg gtagagcagg ggattgaaaa tccccgtgtc
     1621 cctggttcga ttccgggttc gggcaccaca aatttgaaac cctcgcttcg gcgggggttt
     1681 ttgcgtttga gggctttaac gctgtgatgt tgttggggta aggttgattt acgcgatcgt
     1741 aatgttctgg tttacggttt cgatggtcgg cattttcact atgtgatgct gaaagcatat
     1801 gggcggggat ggcacagagg cgcatttcgt cattgccttg cacaacacgc agcttcgccg
     1861 tgtgcgagct gatgagatac cgcagaagcg aattattccc tggataacca agcaggctaa
     1921 acagcaacag gaagctgtat gatgaaacgt acattatttt taggcatctt atatcctgcg
     1981 ttggcattct cagatactcc cggttttatg acacccgaag tggaatgcct caatgacaat
     2041 acgattcctt tcataaacac aaaaattcca gccaaaaaat cgttgacgac gcatacataa
     2101 aatgcaagtc ggaattggat gcctggtcaa aatctcgtga aatgcttcct aaagaaatca
     2161 gagaaagcca atataaagaa tttcatgatt tctatataag aatgatcgag aaaagacggg
     2221 catacgaagc taagaaatag tgtaaattgc tcaaaaagca taaggaagtt ttacagttaa
     2281 tgagcaggct attgctaagc tgactaattt attgaaatat atttcaattt ttaattgtta
     2341 gtccatgtaa aatacatatt tatttaagct atctgagtat cactacactg ttttttatag
     2401 cttatatgtt aattttgagg agtggtttga tttggtaagg gggttatcta tttgtgcaaa
     2461 ggacgggcta atcatatagc taaaataatg aacccgatga aaaattaaaa gcaataaaaa
     2521 actgataata atattaatcc agaaagattt ggttagctta ttgaggtgcg tgcgttctat
     2581 acctgttttt cctgtttctt atattgatga aaaaaccgat tagtgaagct aagcctcttg
     2641 ttacgtagga aacaagataa agcacaaaaa taattttaat tgtgccaggg ctgaaactga
     2701 ctcgtcaaag tcttacgaaa tgtccatcat attaccttca ttcacgctta attggcggtt
     2761 taccgcctcc acgctgtttc tgctcagatc atttgactga cggactcctc cgctgctcaa
     2821 gaagctctgt atgctgagcc gcagaaaatg catcaccttt catctgtccc ctctggcagc
     2881 ctaccgtcga gctcatacat cagcgcgtga gagagtactg gtcgaaggtg ttcgagtttc
     2941 gttagcggag ggaaatcgag ttgtggttgc atcttacctg gggtcagact caggggctac
     3001 ctgaaggtgt ggggctgact taatcgcaac ctgctaaaag gcgtcccttt gagagattct
     3061 gcccgcgccc tgccctgatg caattggaaa ttttctcccg gcagtggcat tgcatgttac
     3121 gcaccagatg gccggaaatg ctgttgaaaa taacttctta accgaaaaaa taatttcgaa
     3181 tgttaattca taaaagggat gtccacactg attacagaca tgtattcgat ttgaacgatc
     3241 gaaatatcgc gttatggact gaagcattta acgatgccat gggggaaccc gcgtggcatc
     3301 ttcaggtcga cgatgcttac ggcccacttt tcgtaccgat caatacgctg gtgcatctga
     3361 aggaaaagtt tggcttcgtc tatgacgcgg gtgtagcggc cgcgcataac agcggccaaa
     3421 agaatacaga ctgctcagcc tcggccgttt tagagggcac catctggtca gcagagcccg
     3481 gcaactatta ctgcatgtcc agaaactggg cgggaaataa caggctgacg attgaggtta
     3541 gccgcacgtc tgatatagct ggtagctccg ccacaaggaa aggagcttta ttaaatcgat
     3601 gtatatcaca tccgatctta agctagtcac tgatgcctgg acgaagcgtc ttttcagtca
     3661 gattcatacg gggacacgca ttgaagagga gtagagctgt cagctggcac cggattgtac
     3721 ggtgcttcag aaccatgaag gagaatgctg actatgaatg tgtgctgcga agagcatgca
     3781 cacattcatt acgttgagcc ctttattaac gcgacctaat ttactatgcc cggtaagcct
     3841 ctggagtgtt tatgaagaat ttgcatagta aaatcaactt actggattca gagagagata
     3901 cggacataca aaccgtagaa cgtcgagagc gttctgtaaa gcgtgcggag cgcaatctgg
     3961 tccaggctga gtgaccgctg tatgaacttt atattcagag agacatactg gtgattaagt
     4021 cttggggaga taaacctaac tggcaggcca tttattatat atcggcccca acacctataa
     4081 agaagaacgt cagaaaggga atttatgctg agcgaagaaa aaacccggaa acatatcacg
     4141 gtactgaatg gaaggatcgt actcactcgg ctgctttcaa cggttatgcc atgaacgaat
     4201 aatgccacca acgttatctg tcccaaaatg cggatcttat cacccaagat gaaaacaggg
     4261 gattcagtaa cagtcaaagt gaggcgtgta agatcaattt atcccccgcc ttaagcaatt
     4321 ttccaaaagt cattatcgtg gagcttgaga taagataatt aacctcggat ataagataaa
     4381 tctcatttac ttggaagtgg cggcacacgg agaacgcttg agtataaaca aattaaaaca
     4441 aagtttatta acaaaagaaa caaattgttt cgtactaaaa gttacatcag aaaatacata
     4501 gagttaaaaa catgaataag tttcatctgt tacatgtttt ttgtggtgac tatcctaagt
     4561 gtaaaagatt gcttttttct aatgtttaat atcgaattgc cgccattaaa tttaatttta
     4621 attaaagttt aacaatgtaa agtgttggtt ttaagggttt ttttgcaaaa ctgacaaaag
     4681 attacacttt gattaacaaa ttgaaatata aattaagttg ataagattgt cgggcgatag
     4741 ctataagata gttcacagac ataagcgtga cggcagtgat aaatcacggt tagtgtttaa
     4801 cattactaat gttgaagcat tttcagtgtc gaaatactcc aaaccagata gccagaattt
     4861 aaaggcgtat tgaataaacg aacgactttt ttcaaaaatt ttttattgat cattttatca
     4921 ccacggaaat gtaaagcgtt taggcaggca ctctataaga gcgtcttaat ttctcatctt
     4981 tacgcatcaa aggtgtttat atgatcaaaa aacttattgc agaaaagggt actctgattt
     5041 ttattgaggc ccataatccg ctctccgcat taattgcgtc taaagcagaa caaactaatt
     5101 cagaaggccg tattgtcaaa tttgacggta tatggtcaag ctcgttaacg gactcagcat
     5161 ctcgcggtat tcccgataac gaaacactgg cattaagcag caggttagaa aatattgctg
     5221 atatccgaaa tgtgacagac atgcccatca tcatggatgc tgatacgggg ggaaaaccag
     5281 aacattttag ttattacgta aaaagaatga ttaacaacgg tgtaaatggc gtcatcatcg
     5341 aagataaaac aggattaaag aaaaattctt tgttcggcac tgaagtagaa cagactctcg
     5401 cagatattaa tgatttttca gagaagatta aaagaggaaa atctgcagtt tatattgatg
     5461 attttatgat catagccaga cttgaaagtc ttattgcagg gttcgacgta gaacatgcac
     5521 tcgaacgtgc cgacgcatac gtcgaagccg gggcagacgg aattatgatt catagttgta
     5581 agaagactcc ggatgaggtt ttcttattca gtacgaaatt tcggaaaaaa tatccatcag
     5641 taccattaat ttgtgttcct actacttatt ctgcaaccag caacagagaa ctcagtgaag
     5701 cgggttttaa cgtgatcatt tatgcaaacc atatgctcag ggctgcttat aaagcaatgg
     5761 aaaatgtttc aaaagaaata ttgagatatg gcaggacggc agagatagaa aaatcttgca
     5821 tgagtgtaaa ggaaattatt tcactgattc cttaaagaga atgaccatga aaaaaaaaga
     5881 gatgataata ggtgcctata tatcgtatgg aacaggacat catcctgctt catggcgcga
     5941 aagtggcgta aatgcagcgg cagcgcttga tattgatacg tatgccaatc ttgcaagagt
     6001 atgtgagaaa ggattagctg atttactttt tcttgcagat acgccttctg tatttcagga
     6061 caatatggac ggttatggca gcagggtatc tgtactggag ccattatcat tattatcgta
     6121 tttagcatct caaacacaaa atattgggct ggttgcgacg gcttcaacga cgtacaaaca
     6181 cccttacaac attgcgaggg aatttgcttc gctggattac attagcaaag gaagggcagg
     6241 gtggaatctg gtgacatcct caaagtcgga tgcggctaaa aactttggcc ttgccgctca
     6301 tccagaacat tcaaagcgtt atgatatggc ctgggaagca tggcaggtta tcagtggttt
     6361 gtgggacagc tgggaagaca atgctttagt aaggaataaa accagtggac aattcttcgt
     6421 taaggataaa taccgggaaa taaattttga gggtgaatat tttaatgtaa aaggcccatt
     6481 aaacatagct cgccctcctc agggctatcc cgtcatcgtc caggcgggtt cctctgagga
     6541 aggaaaagag ttagctgcaa aaacagcaga tattgttttt actgcacaaa acaatattga
     6601 agatgcaaaa aaattctatg atgatcttaa agggcgaatg gaaaaatacg gaaggtcaaa
     6661 gagtgaactt cttattcttc ccggattaag cttttatatt gcaagtgacg aatctaaagc
     6721 ccgtaaaaag cttaatgatc tcaacgcact gatccctcaa tcatttggct taagtatgtt
     6781 atcagattta ctgggtgggg ttgatttaaa aaacaatgat cctgaaggac cattaccaga
     6841 tttaccgaaa tctaatggta atcagagtag acaaaaaatt attatcgatt tagctcgaaa
     6901 agaaaaacta tctatcaagc aactttatga aaaaataatc atttcaagag gacattatac
     6961 atttacaggt tcctatcaag atttagcaga tgagatgatt aagtgggttg aaaatgaagc
     7021 atgtgatggt ttcaacatta tgcctcctct catgcctgaa tctcttatta atcttttcga
     7081 tcatgtcatt ccacttattc aggcaagagg atggtataaa aaatcatatt ctactggaac
     7141 attaagagaa aaactggggc ttaaaagacc tactaataaa ttgtttaatc aataatgtat
     7201 tgcgaggaaa tataaaatgc ttaataaaaa tctgattctt gaagatacca ctttacgtga
     7261 tggtgagcag gcgccaggtg ttgcatttac accagagcaa aaagtagaaa ttttttatct
     7321 acttgcaaat atgggcgtta aatggatcga agccggaata cctgcgatga agggtgatga
     7381 agtaaaggct ctgtcggaaa tgttagagag aaaaaatgaa attaacatca tcgcgtggaa
     7441 ccgaggcgtg cttgaagaca ttgagtacag tatctcactt ggattcaaag cggtgcatat
     7501 cgggctaccg acttcagcta tccatttaga gaaaagcgtt aagaaagata agtcctggct
     7561 tgtaaagacg gcttcagatt tagttaagtt tgccaaagac aaagggatgt ttgtttctat
     7621 cagcgcagaa gatataggcc gaacagatat tggattctta caggagtatg cacaggtagt
     7681 tgctgaggct ggagccgatc gtcttcgcct ctctgacacg attggtattc tttctcctgc
     7741 acaatacaaa gaaaaagtct ctttgttaaa taagaacgtc aacatcgatt tgcagtgcca
     7801 ttgccacaat gattttggtt ttgcagttgc taacacgctg gcaggcattg aagcaggagc
     7861 acgctacttt catgtctgcg tcaatggcat tggtgaaagg gctggaatgc cagacctggc
     7921 acaagttgct atggcattgc actttttcca cggggttgat ttagggctcg atttaacaaa
     7981 attaatcgcg ttgagtgaaa cggtcgccag gtacagccat caaaaaatca gtccatggca
     8041 gccgatcgta ggcgataacg tttttgcaca tgaatcgggc attcacgcaa atggtatgct
     8101 caaagacagc agtacttttg aacccttcga cccagctacg gtgggaggag aacgacgtct
     8161 ggtcgtgggt aaacattccg gtcgcgccat tatcaaacat tttctcgaag aatcaggcgt
     8221 gaaagctgcc gacgataagg ctcttgatcg ctgtttagaa cgcgtgagaa gtcatgccgt
     8281 gcgccacccc ggtgggatcc ctccacatgt attagttgat ctgtataccg cggggtaaac
     8341 aggtatgaaa agtaatcagc cgattgttaa ccagatcatt gcgtcacaca gtggcagagg
     8401 tcaggtttca gcaggtgaac tgatcacggt agatgttgac tacgtctatg ttcaggatgg
     8461 aaattcaccg accgtggcaa aactgtttca ggattatcat ctgtctgagg tgctaaaacc
     8521 cgataaaatc gggttcttct tcgaccattc agttctggta cctgataaaa ccatggctaa
     8581 acgtgtcaac gaggccatgg aatttgcaaa aaaacttgga ataaacatct attcacgagg
     8641 ggagggaatt agtcacgtca ttgccctgga gagtaaaata tttaaacccg gcaatatagt
     8701 gctgggcgca gattcccata cttgtacagg gggggccgta cagtctttag cgctgggaat
     8761 gggggcttcg gatattctgg ttgctatgtt aacaggacaa acgtggttga aagtccctca
     8821 aacagtccat ttgtgtatta agggtaaaac gggaaaagat gtgcgggcaa aagatgtcat
     8881 gttggcactt ttaaataagt acggacaaac accatttctt tataaatcga tcgaagtttc
     8941 aggggaatgg gcagaagagc taacgcttga cgaagctgca agttttgcaa gtatggctgt
     9001 tgagttagga gccaaatgca tatttatgcc agatgggcaa ggcaggcctg aggggctatt
     9061 gaaggcggat gcctcagtgg cagacagtgt catcaatttt tctgtatcag aattaatgcc
     9121 ccatatcgca ccacctcaca gtcctttgta tgctaaacct gcaaatgact ttgagggtct
     9181 gaaatttgat tatattttca ttggaagctg tactaacagc agacttgaag atatcaaaga
     9241 ggtggccgaa attgttgctg gtaaaacaat acatcccgat attcactgcc ttctgacgcc
     9301 aggatcgaaa agtgtttatc taaaagctct ccaggcggga tatatcgata cgcttatccg
     9361 ctcgggcatt attgtcaccc caccgggttg tggagcttgt gtgggtaccc aaggaaccat
     9421 tcctgcggat ggggagaaag tattaagtac gatgaaccgc aattttaagg gaagaatggg
     9481 gaatgctgag gcagacatct ttttatgttc tccacgaact gcagcgatgg ttgcattgaa
     9541 cggcactgtt ccacattttg agggagagtc cgcatatgag taaaactgct gaaaattatc
     9601 gcgtcagacg cgtggaaggg aacatctcga ccgacgatat tatacctgcg cgctataaac
     9661 atatgtatac cgagccggcc cagctggcac cgcatctttt tgagagccgt tttcccggat
     9721 ttagggaaac gctcagtatc aatgatgtgc ttgtatgtga tcaaatattc ggtataggga
     9781 gttcgcggga gcaggcagta acaactctgt tggcatgtgg tgttaaatat gtattttccc
     9841 cttctttcgg gaggattttt tttaggaact cttggaattt gggtttacat gcgattgagg
     9901 tcgatacgag tgaacttgca gatttaagtg aaattaaaat agaactgact ggaggggtaa
     9961 tttatacaga aaataatcaa ataaattttt tccctcccag ctcgcagatg acggcaattg
    10021 tcagtgcagg tggcataata ccctacacca taaataaaat tatggaaaaa aaaggtgata
    10081 ttttaagagg ttatagcaat gaaaagtgaa aagtttgatg gtttggctga taactatgat
    10141 aaatatcgtc cccgttatcc tgcaatcctt ttcaaggaaa tccatgactg gatgcagccg
    10201 tctgccaaaa atatatacga tattggcgca ggcacaggta ttgctattga aggtatgaca
    10261 cgtgtcactg gaaaacacta tgatttcacg gcgatagata tttctgaaga tatgataaaa
    10321 aaaggaaggg aaaaactgcc tggtacgact tgggttaaag gaaaagcgga agatattctt
    10381 tctgataaaa gccgtattga cgtcattatg gcggcacagt ccttccaatg gatggataga
    10441 gctaaaacat tagaagtttc gataaaatct ttaaataagg gcggggtttt tgcagttttg
    10501 caaaacaatc gagattacag aaataatgaa atgcttaaca aatatgaagg tttgctagag
    10561 aaatttagtc caggttacag cagacattat cgcgactatg actatgaaaa tgaaatcacc
    10621 aatgttttta aattgcctat tgctaacttt aagaaagtcg tcacagggtg gactatggaa
    10681 atgatttcag aagatttttt tggattcatt tcttcctcaa cccaggtaca aagagctatt
    10741 gagaacgatc gtaatggatt ctggaaggag attgaaatct tgattgacga acactcagtt
    10801 ggtggaaaaa ttagcataga ttatataagt gagttattta tagctaagaa gcgtgatgat
    10861 tcatagcatg acgattcagg acatcagcat tgaacaagct tcgtatgaag atgcgaagct
    10921 gttaagaaag gctttagaaa aagtttacga accttataca ctgaatttct cacctaccgc
    10981 tttgcagttt actgaaaata tcattgctca ggaatcctcg aagtggctag tcgcgaaata
    11041 caagtcagac attgtggggg cagtgagata tgaactttat gatatttatc tggacttcca
    11101 ttttctctgc gtcacaccac cattcagaaa aatgggagta gggaatgaat tatttcataa
    11161 actgaagaaa atagcgtatg aaaaaagaaa ggattttatg aagatcgttt tgcgagattc
    11221 gctaagctat aaccgacgct attttgaaag taaaggattt tacttttatc ataaatacca
    11281 gacaaatatg catagtgtat ttattttaaa attaaacggt gaaaagccat gaataaaaaa
    11341 gcattggtta ttgggttgaa aagtaatatg gaaagagtca tcaaagggct caatgagata
    11401 gaatttatta ttattgacag aggaacactg gataacgaaa gtatagatta tatcattaat
    11461 ctttcagatg atttaatgca taaaaaatca ttcagttatg ttatagccag ttctgaggat
    11521 tttatcgctt tggctgggtt attgcgtaat cgttattcac tttatggtga aaaatattat
    11581 aaaagtacaa ttgcaaccaa taaattcctg atgcgtaatt tttgctcagg ttttttatcc
    11641 tgtcccaagt tctggctatc aggtgagatc atcaattcag agaatctttt actgtcatcc
    11701 cagaaagatt acatcgtaaa acctcttaca ggtagttctg caaaacatgt cgaaacagtc
    11761 acacaggaag acttaaacca atatcttaat gaaaataaca aattgatgtt aattgaagaa
    11821 aaggttttaa tgagagatga atatcatctt gattgtataa tcaaagacgg taatatcctc
    11881 ttttcaacac tgtcaattta cgacaggcct atactcgagg caaaaagtaa aaacagagcc
    11941 agtatcaact tacccgatgg cacacggctt catgaagatg ccttaatact tgccacgaat
    12001 ttgcaaagtc attttgaaat gactaatggc gtttttcata ttgaaatgta tcatactcag
    12061 gatggattta tactcggtga gtttggtatc cgccctcccg gagcgggtgt gaccgatatg
    12121 tattatatgt atagaggcgt cgatttctgg gaggcattta tttattctca gattgataaa
    12181 gaatttattt tacccctaaa tcataagtcc gataaatatt gtgctgctat tgggatatgt
    12241 tcttctttcc cggtcgatga tatcagaagt acgtcaaaag tatccgtgga taaatatgta
    12301 aatttgcgtg agaatgctgc taaacccgca gttcccagtt caacgtcttt taatcatatg
    12361 atttatgttt cttcatcatc cttagaagaa ataaggaatt ttttgcatga tatttctgac
    12421 agacaagagt aagattcgat atgttaaaat atgaaaccaa aaaaaacgct ttcttccaga
    12481 tatacaattt tctttcatgc tcggctgaag ggattcagac ggttatattt ttgtggctta
    12541 tatatcatga aactcatagt ccgatgcttg tcagtctgac tatagtttct tcatatcttc
    12601 catcagccgt attaggattc tttttcctca aaaaagctga tgcgagcagt cctggaaaac
    12661 agttatttat cagtaatgtt tctcttagtg ccatatcgct aattgtctat tttattttaa
    12721 tgagaaatga gggttttgaa ctaatcacgc tcagtatctt ttatttggca caggccgtat
    12781 tatctgttgt caaaatgttt aataagacat cccaaaatcg cattatcaga acagcattca
    12841 gtaatagtga tgcaataaaa gcacttcagc ttgcctcctc tggcatgcag gccgctcagg
    12901 tttttggcgc ggccatagga ggatgggcta tcagtacggg ttactacatg caagcgctca
    12961 tgctgacctg ctgcatctac cttttgaata tttatatttc gacacttttt gagaaaggga
    13021 atcctgataa taaagacgct gaggttattg tgcagattca ctctgtcact aagaaaaatg
    13081 aatcctttac atatcttttt cgcagtaagg actttttgtt acccttgatt tttactgttc
    13141 catcaagtgg agctttacaa tttttaaaca catcccttcc ttcattatct tctctatatg
    13201 gtaatagcga gaaaatttat ccagtgctga atatgactct acaatgtgct gtcattatct
    13261 cggggatagc agcagcactc aatatgcttt ctctaaagtc ttcattacgg ttttctctgt
    13321 gtatttctgg catctgtc
//
