LOCUS       KV830731.1             10068 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  KV830731.1 Staphylococcus sp. HMSC062C03 genomic scaffold
            Scaffold143, whole genome shotgun sequence.
ACCESSION   KV830731
VERSION     KV830731.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.0.0
            Run date     :: 2023-10-04 11:22:19
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10068
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10068
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[70:5068]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      71..5068
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     cand_cluster    1..10068
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10068
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NI-siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     gene            complement(71..2020)
                     /ID="gene-HMPREF2699_06085"
                     /Name="HMPREF2699_06085"
                     /gbkey="Gene"
                     /gene_biotype="protein_coding"
                     /locus_tag="HMPREF2699_06085"
                     /source="Genbank"
     CDS             complement(71..2020)
                     /Dbxref="NCBI_GP:OHP71799.1"
                     /ID="cds-OHP71799.1"
                     /Name="OHP71799.1"
                     /gbkey="CDS"
                     /gene="HMPREF2699_06085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011275171.1"
                     /locus_tag="HMPREF2699_06085"
                     /phase="0"
                     /product="sialic acid synthase"
                     /protein_id="OHP71799.1"
                     /sec_met_domain="IucA_IucC (E-value: 8.1e-67, bitscore:
                     215.4, seeds: 168, tool: rule-based-clusters)"
                     /source="Protein Homology"
                     /transl_table=11
                     /translation="MDNLISIDNIDLHLTDEELGALSFLKQEMPHLVNYFKNELLVARD
                     KISQRLITSLYRENLVNAKSNSTFVSSCDIKNFPINGEHQIMRVHFPESDKYLFAKVSS
                     THAFGRVDVEGPFYYCDSDGRQCVRILHPNEVLADILKENPELDNEASSQFKDDMENSV
                     ANMALALSYQAYEMQHSKEPLLEIIINEQDSYLRSEQAVIEGHPLHPGAKLRKGLNANE
                     NIKYSSEYNKEIHLKCVLIHQSIARTQSLSFTYDAELEAQFPELYSQIKTECDNLSNLS
                     EYHLMIVHPWQLDNVLLSQYEEEINNNLMIPLKIEIPYYAGLSFRTLMPKFPSTLPHIK
                     LSTNVHITGEIRTLSEQTTHNGPLVTQILNDILKQDKNFTHYRVGILNEFAGIHFYNSN
                     DEEAIQTDLSEQLGTLFRDNVYNLTEKDSIPMIPSSLVVTYKYNEEPPIISLIQRYKHH
                     YDKSNLDIAAQEWLSDYISQLLGIVIPLYAKYGIALEAHLQNSISTFNADGRLNTIYIR
                     DFEGLRIDEQLLNETGYTTKHFHEKSRILTDSKTTVFNKVFYSTVQNHIGELILTVSKF
                     IEDEEFESKLWDSVSEIIHNILNSLTDINTSRISEIKQIMFDRDIDYKCVTTMRLEDEA
                     HHYTYIKVSNPLHG"
     gene            2135..3304
                     /ID="gene-HMPREF2699_06090"
                     /Name="HMPREF2699_06090"
                     /gbkey="Gene"
                     /gene_biotype="protein_coding"
                     /locus_tag="HMPREF2699_06090"
                     /source="Genbank"
     CDS             2135..3304
                     /Dbxref="NCBI_GP:OHP71800.1"
                     /ID="cds-OHP71800.1"
                     /Name="OHP71800.1"
                     /gbkey="CDS"
                     /gene="HMPREF2699_06090"
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 173.9; E-value: 8.3e-53)"
                     /gene_kind="transport"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011275172.1"
                     /locus_tag="HMPREF2699_06090"
                     /phase="0"
                     /product="multidrug MFS transporter"
                     /protein_id="OHP71800.1"
                     /source="Protein Homology"
                     /transl_table=11
                     /translation="VAKFFFSSSFLLFLGNWIGQIGLNWYVLTSYHNAVYLGLVNFCRL
                     VPILLLSVWAGAIADKFDRGKLLKMTISSSFLVTSTLCVCTFLLEQVPIIFILIYATLR
                     GMINATETPIRQAVLPDLSVHLNTSQAVSYHSFIINICRSIGPAIAGLILSIYHAPFTF
                     LAQSMCYFIAVLLCIPLTFKTVGEANKANKGFSFTVVWEYFKNNMQASRIFITSLIIMA
                     TGFSYTTLVPVLVHDLFPGRSEIFGVSMTFCAVGGMIATLLLPIILKKFTIVQMYYLSS
                     CLFGLALVGVIIHNIIFMFICMSLVGLFSQLARTSNRIYFQEDIASEHRGKILSIVMMD
                     RGMIPLGSLILTTLSEIMGPINTFITMGIFTFVIAFIAYIIQRPIKLEE"
     gene            3308..5068
                     /ID="gene-HMPREF2699_06095"
                     /Name="HMPREF2699_06095"
                     /gbkey="Gene"
                     /gene_biotype="protein_coding"
                     /locus_tag="HMPREF2699_06095"
                     /source="Genbank"
     CDS             3308..5068
                     /Dbxref="NCBI_GP:OHP71801.1"
                     /ID="cds-OHP71801.1"
                     /Name="OHP71801.1"
                     /gbkey="CDS"
                     /gene="HMPREF2699_06095"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011275173.1"
                     /locus_tag="HMPREF2699_06095"
                     /phase="0"
                     /product="siderophore synthetase"
                     /protein_id="OHP71801.1"
                     /sec_met_domain="IucA_IucC (E-value: 4.1e-57, bitscore:
                     183.7, seeds: 168, tool: rule-based-clusters)"
                     /source="Protein Homology"
                     /transl_table=11
                     /translation="MTQNAWQNADTNIQYRILNALIKENIWQEQTIITTKDDQLDIQYH
                     GCILSTHFNHNSVMSRYEFVGPITFRCGTNIMEVSTVEALLDMLSNHFDINIHQQLIDE
                     IIHSRDSFVEIYKQFYQRQHNVQSSMQFSGMPTTLNFFAWLQHLNDANEINDLLYSESL
                     VLEGHPTHPLTKTKLPLTMDEVKMYSPEFEKVIPLKIMLIHKDCAQATCIDNDEDFILK
                     KVIPEYQTRIRKYAQSIHISLEDYFVILVHPWQYNHTIYDKFANWIANKFLLTTPFDVD
                     SKATLSFRTMALINKPYHIKLPVNVQATSAVRTVSSVTTVDGPILSSALQNVLNQYPQL
                     NVALEPYGLCAKTNDEDARQLACIVRETPYIANNGVTIVTGALVNPNPIDRHITVDSYI
                     EWVNGELNNRGILTFIQNYSRQLITPLINLIQEYGIALEAHMQNTIVNLGPNYQMNFIV
                     RDLGGSRIDLNTLTHKLKNINVSNQSLLANSIEEVIAKFQHAVIQNQLAELIHHFSKTE
                     FVTEEELFTLVQDEVKLAINDNKPHAQALKDVLFGSKITVKALLRMRMSNRVKKYLNIE
                     LDNPIRDEVR"
     gene            5069..6136
                     /ID="gene-HMPREF2699_06100"
                     /Name="HMPREF2699_06100"
                     /gbkey="Gene"
                     /gene_biotype="protein_coding"
                     /locus_tag="HMPREF2699_06100"
                     /source="Genbank"
     CDS             5069..6136
                     /Dbxref="NCBI_GP:OHP71802.1"
                     /ID="cds-OHP71802.1"
                     /Name="OHP71802.1"
                     /gbkey="CDS"
                     /gene="HMPREF2699_06100"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011275174.1"
                     /locus_tag="HMPREF2699_06100"
                     /phase="0"
                     /product="alanine racemase"
                     /protein_id="OHP71802.1"
                     /source="Protein Homology"
                     /transl_table=11
                     /translation="LAQININLSKIEYNADALRTLLENNDIHLTPVIKCIAGDSRIIET
                     LIQSGFTHFAESRLENINEDFKGQCNYLLLRPTSKNRYTQLIKSVKMSMQTEIESIREI
                     NDIAKQLNQKHQIMLMIDWKDRREGVITYDVLNYIEEIIKMTHIQLIGIAFNFMCFKSS
                     APTEEDILKINQFVDAIEYNLGFRLKVVSGGNSSMIPQLMYNDLGRINELRIGEALFRG
                     IDTTTNQSIPMLFQNAITVEAEILEIKPRLSDNNQCYLQAIVDIGYVDTDVNKIKPIKN
                     DVSIVGASSDHLMINLNNQDYYKVGDIIEFAMEYEALSQVMYHNHMTKHYFKDNYIQSL
                     NSMMVDSPLLINKKC"
     gene            6377..7375
                     /ID="gene-HMPREF2699_06105"
                     /Name="HMPREF2699_06105"
                     /gbkey="Gene"
                     /gene_biotype="protein_coding"
                     /locus_tag="HMPREF2699_06105"
                     /source="Genbank"
     CDS             6377..7375
                     /Dbxref="NCBI_GP:OHP71803.1"
                     /ID="cds-OHP71803.1"
                     /Name="OHP71803.1"
                     /gbkey="CDS"
                     /gene="HMPREF2699_06105"
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 251.1; E-value:
                     2e-76)"
                     /gene_kind="transport"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011275175.1"
                     /locus_tag="HMPREF2699_06105"
                     /phase="0"
                     /product="iron citrate ABC transporter substrate-binding
                     protein"
                     /protein_id="OHP71803.1"
                     /source="Protein Homology"
                     /transl_table=11
                     /translation="MKGFKFAGIVALLFALVLVTACGNVSNNGSGDSGNKSSSKDSIKI
                     KHELGTTKVPKDAKRVVALEFSFVDALAALNVKPVGVADDNKPNRIIKPLKEKIGDYKS
                     VGARKQPNLEEISKLKPDLIIADSNRHKGIYKELSKIAPTIELKSFDGDYNDNIDAFKT
                     IAKALNKEDEGKKRLDEHKEKIAKYKDEIQFDKNEKVLPAVASKSGLLAHPSESYVGQF
                     LSQLGFKEALNKDVTKGLSKYLQGPYLQLNAETLKDVNPERMFIMTDGASPKEPSYQEM
                     KKDPVWDTLDAVKHNRVSIVSRDTWARARGLISSEEMAKELVEISKKDKEK"
     gene            7388..8419
                     /ID="gene-HMPREF2699_06110"
                     /Name="HMPREF2699_06110"
                     /gbkey="Gene"
                     /gene_biotype="protein_coding"
                     /locus_tag="HMPREF2699_06110"
                     /source="Genbank"
     CDS             7388..8419
                     /Dbxref="NCBI_GP:OHP71804.1"
                     /ID="cds-OHP71804.1"
                     /Name="OHP71804.1"
                     /gbkey="CDS"
                     /gene="HMPREF2699_06110"
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 295.1; E-value: 9.3e-90)"
                     /gene_kind="transport"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011275176.1"
                     /locus_tag="HMPREF2699_06110"
                     /phase="0"
                     /product="iron-siderophore ABC transporter permease"
                     /protein_id="OHP71804.1"
                     /source="Protein Homology"
                     /transl_table=11
                     /translation="MTIRSTDSQSALDKANKRRTTLTFIVSGCFLFIFAYFNLAIGSSE
                     IHAKHIFEYFFTSINNKQTFLIHNVRMPRMIGGLLIGGALALAGLLMQAITRNPLASPQ
                     IFGVNSGASFVIVLVTILIPSLGNYATYLAFLGAFIGGLTVYVLSGSTKKITPIKLALA
                     GMAIHLFFSSLTQGIIILNEDSNTTVMFWLVGSLNGLKWTAVLSVMPLLILALIITMLL
                     GRQLTIMELGDDIAKGLGQKTQLIRIIVGLLVIVLAGASVSIVGPIGFIGLIVPHIVKR
                     YISKDYFLMVPLTFLIGADLLLLSDMLSRLITFPYESPVGIVTSFVGAIYFLLITLKGV
                     KRI"
     gene            8416..9381
                     /ID="gene-HMPREF2699_06115"
                     /Name="fecD"
                     /gbkey="Gene"
                     /gene="fecD"
                     /gene_biotype="protein_coding"
                     /locus_tag="HMPREF2699_06115"
                     /source="Genbank"
     CDS             8416..9381
                     /Dbxref="NCBI_GP:OHP71805.1"
                     /ID="cds-OHP71805.1"
                     /Name="OHP71805.1"
                     /Note="Ferric citrate binds FecA and is transported across
                     the outer membrane while transmits a signal across the
                     cytoplasmic membrane protein FecR. FecR transmits a signal
                     across the membrane and activates the cytoplasmic FecI that
                     directs the RNA polymerase to express the fecABCDE operon
                     (which encodes the ferric citrate outer membrane receptor
                     and the ferric citrate ABC transporter), as well as fecIR.
                     FecD is one of two (along with FecC) integral membrane
                     protein components of the iron dicitrate ABC transporter."
                     /gbkey="CDS"
                     /gene="fecD"
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 265.7; E-value: 8.1e-81)"
                     /gene_kind="transport"
                     /inference="EXISTENCE: similar to AA
                     sequence:RefSeq:WP_011275177.1"
                     /locus_tag="HMPREF2699_06115"
                     /phase="0"
                     /product="iron-dicitrate transporter subunit FecD"
                     /protein_id="OHP71805.1"
                     /source="Protein Homology"
                     /transl_table=11
                     /translation="MTKRQLSIRYTVVIICLIVSIFISLCVGSTMYSPLKAIHGILKFD
                     DFILNEYRIPRTLLGLVVGSSLAISGAVIQGVVRNPLASPDVIGITKGASLAAIIVIML
                     FPSAPLLVLPIGSFIGALFISLILSFLISKYNIKGSTLALIGLAIGAICTAVVQFLLIR
                     NPMDANNALVWLTGSLYGHTIENFYSVIPWFVITLPLVLCLSYQLDILNLGEHIATALG
                     ARVQRLKMILLILSVMLAGASISVVGGISFLGLIAPHIARSIVGLRYFHVVIMSGCIGS
                     ILILFSDGLARGIHPPLDIPVGVIIAIIGVPYFLFLLRRI"
ORIGIN
        1 ctatttctct agggtttatg tcccagactc tttttttatt ttagaattaa gttttgattt
       61 ctaatatcgt ttaaccatgt agtggattac ttactttaat ataagtatag tgatgtgctt
      121 catcttctaa acgcatcgtt gtcacgcatt tataatcaat gtctctatca aacataattt
      181 gtttgatttc tgaaatgcgg cttgtgttaa tatccgttaa gctatttaaa atgttatgaa
      241 taatttcgct tacgctatcc cacagtttag attcaaattc ctcatcttca atgaattttg
      301 aaacagttaa tataagttca cctatatgat tttgaactgt cgagtaaaag actttattaa
      361 atactgttgt tttagagtcg gtcaagattc tagatttttc gtgaaaatgt tttgtcgtat
      421 atccagtttc atttaaaagt tgttcatcaa tacgtaagcc ttcaaaatca cgaatataaa
      481 tagtgtttaa tcgtccatca gcgttaaacg ttgaaattga attttgtaaa tgtgcttcaa
      541 gtgcaatgcc atatttagca tataaaggaa tcactatgcc taacaattga gaaatgtaat
      601 ctgacaacca ttcttgagct gcgatatcaa gattagattt gtcgtagtga tgtttataac
      661 gttgaattaa actaatgatt ggtggttctt cattatattt ataggtaacc actaaacttg
      721 atggaatcat aggaatacta tctttttcag ttagattgta cacattgtcc ctaaaaagcg
      781 ttcctaattg ttcacttaga tctgtttgaa tagcttcttc gtcatttgaa ttataaaagt
      841 gaataccagc aaattcattt aaaataccaa ctctataatg agtgaaattt ttatcttgct
      901 ttaaaatgtc atttaagatt tgagtaacta aaggaccatt gtgagttgtt tgttcagata
      961 aagttctaat ttcgccagta atatgtacat tggtagataa cttaatatgt ggcaacgtgc
     1021 ttgggaattt cggcattaaa gttctaaaag ataaaccagc gtaataaggt atttctatct
     1081 ttagtggaat cattaaatta ttatttattt cctcttcgta ttgacttaat aatacattat
     1141 ctaactgcca aggatgaacg atcattaaat gatattcact cagattactc aagttatcac
     1201 attcagtttt aatttgacta tatagttctg gaaattgcgc ttctaattca gcatcataag
     1261 taaaagataa agattgtgtt ctagcgatac tttggtgaat aagcacacac tttaaatgga
     1321 tttctttatt atattctgaa ctatatttaa tattctcatt agcattaagg cctttgcgca
     1381 atttagctcc aggatgaagc ggatgtccct ctataactgc ctgctctgaa cgcaaataac
     1441 tatcttgttc attaataatt atttccaata aaggttcctt tgaatgttgc atctcatatg
     1501 cttgatatga aagtgctaac gccatatttg caacactgtt ttccatatcg tctttgaatt
     1561 gtgaacttgc ctcattatca agctctggat tttcctttaa gatatcagct aatacttcat
     1621 taggatgaag tatacgaaca cattgtctac catcactatc acaatagtaa aatggacctt
     1681 caacatctac acgaccaaat gcatgagtac tggaaacttt tgcgaataaa tatttatcgc
     1741 tttcgggaaa atgcacgcgc ataatttggt gttctccatt tattggaaag tttttaatat
     1801 cacatgacga gacaaaggta ctatttgatt tagcgttgac taaattttct ctgtaaaggg
     1861 atgtaattaa gcgttgagaa attttatctc gtgcaacgag caattcattt ttaaagtagt
     1921 ttactaaatg gggcatttct tgttttaaaa acgataaagc tcctaattct tcatcagtta
     1981 aatgtaaatc tatattgtct attgaaatta aattatccat atggcacctc aaattcattt
     2041 tacaaaaatc taaaacattt gtataatcca taatatcgat aatgatattc attatcaatt
     2101 ataaatatta ttataaataa gtaggtggaa tactgtggcg aaatttttct tctctagttc
     2161 ctttttatta tttctaggga attggatagg acaaattggc ttgaattggt atgtacttac
     2221 tagttatcat aacgcagtct atttaggatt ggttaatttt tgccgactcg taccaatttt
     2281 gttactaagt gtctgggctg gcgctatagc tgataaattt gatagaggaa aattattgaa
     2341 aatgaccatt tcatcttcat ttttagtgac aagcacatta tgtgtttgta cctttttatt
     2401 agaacaagtg ccgattattt tcatcctcat ttatgccaca cttagaggta tgattaatgc
     2461 gacggaaaca ccaataagac aagctgtatt gccagattta tctgtacatt taaatacaag
     2521 ccaagccgtt tcatatcatt cttttatcat aaatatatgt cgctcaatag gtccagcaat
     2581 tgcaggattg atactctcaa tttaccatgc accgtttact ttcctagcgc aatcaatgtg
     2641 ttacttcatt gctgttctat tgtgtatacc attaaccttc aagacagttg gtgaggcaaa
     2701 taaagctaac aaagggtttt catttacggt tgtgtgggaa tactttaaga ataatatgca
     2761 ggcctcaaga atatttatta cgtcattgat tatcatggct actgggtttt cgtatactac
     2821 actagtacca gtattagtac atgatctctt tcccggtcgc tcggaaatct ttggtgtgtc
     2881 aatgacattt tgtgctgtag gtggtatgat tgcaacactt ttactaccca taattttgaa
     2941 aaagttcacc attgtacaaa tgtattattt aagttcttgt ctatttggat tagcgcttgt
     3001 aggtgtcatt atacataaca ttatattcat gtttatctgc atgtcacttg taggtttatt
     3061 tagtcaatta gctagaacat caaatcgaat atattttcaa gaggatatag catcagagca
     3121 tcgaggaaaa atattaagca tcgtcatgat ggatagaggg atgattcctt taggtagttt
     3181 aatattaaca acattatcag aaataatggg acccattaat acatttatca ccatgggaat
     3241 atttactttt gtaattgcat ttattgcata tataattcaa agaccaatta aattggagga
     3301 gtagagtatg actcaaaacg catggcaaaa tgcggatacc aatatacaat atcgtatttt
     3361 aaatgcttta ataaaagaaa acatttggca agaacaaact attattacaa ctaaagatga
     3421 tcaattagat atacaatatc atggatgtat actttctact cattttaatc ataacagtgt
     3481 aatgtcaagg tatgaatttg taggaccaat tacatttcga tgtggcacaa acataatgga
     3541 agtatcaaca gtagaagctt tattagatat gttaagtaat cattttgata ttaatataca
     3601 tcagcaatta atagatgaaa taatacatag tagagatagc tttgttgaaa tttataaaca
     3661 attttatcaa cgtcaacata atgtgcaatc tagtatgcaa ttttctggta tgccaacaac
     3721 tttaaatttt tttgcatggt tacaacattt gaatgacgcg aatgaaatca atgatttgtt
     3781 atattcagaa agcttagtat tagaaggtca tcctacacat ccacttacta aaacgaaact
     3841 gccattaact atggatgaag ttaaaatgta ttcacctgag tttgaaaaag ttataccgtt
     3901 aaaaattatg ttaatccata aagactgtgc acaagctacg tgtatagata atgatgaaga
     3961 tttcatattg aagaaagtaa tacctgaata tcaaacaaga attagaaaat atgcacagtc
     4021 tattcatatt tcgttagaag actattttgt gatattagta catccatggc aatacaacca
     4081 tactatctac gataagtttg cgaattggat tgctaataag tttttattaa caacaccatt
     4141 tgatgtcgat tcgaaagcaa cactatcatt taggacgatg gcgctcatca ataagccata
     4201 tcatataaaa ttacctgtca atgtacaagc aactagtgct gtcagaacag tttcaagtgt
     4261 tacaacggta gatggaccta tattgagtag cgctttacaa aatgtattaa atcaatatcc
     4321 acaactaaat gttgcattag aaccttatgg tttatgtgcg aaaacaaatg acgaggatgc
     4381 tagacagtta gcatgtattg tcagagaaac accttatatt gcaaacaatg gggtgactat
     4441 tgttactggt gcattggtta atcctaatcc aattgatcga catattacag ttgatagtta
     4501 tatcgaatgg gttaatggtg agttaaataa tagaggtata ttaaccttta ttcaaaatta
     4561 tagtcgacaa cttattacgc ctttaatcaa tttaattcaa gagtatggca tagctttaga
     4621 agcgcatatg caaaatacta tagttaattt aggacctaat tatcaaatga attttattgt
     4681 gcgtgattta ggtgggtctc gtatcgattt aaatacactt acgcataaac tgaaaaatat
     4741 caacgtgtcc aatcaaagtt tattggcaaa ttcaattgaa gaagttattg cgaaatttca
     4801 gcatgctgtt attcagaatc agttagctga attaattcat cacttttcaa aaacggaatt
     4861 tgtaactgaa gaagaattgt tcactctagt tcaagatgaa gttaaattag caataaatga
     4921 taataaacca catgctcaag ctttaaaaga tgtactcttt ggttcaaaga ttactgttaa
     4981 ggcattatta cgcatgcgta tgagcaatag agtgaaaaaa tatttaaata tcgaacttga
     5041 taatccaatt agagatgagg tgagataatt ggctcaaatc aatataaact tatctaaaat
     5101 tgaatataat gcagatgcac taagaacgtt attagaaaat aatgatatac atttaacccc
     5161 agtaattaaa tgtatagctg gtgatagtcg aattatcgaa acattaattc aatcagggtt
     5221 cacccatttt gcagaatcaa gacttgagaa tataaatgaa gatttcaaag gacaatgcaa
     5281 ttatctttta ctaagaccaa catctaaaaa ccgttatact caactgatta aatcagtgaa
     5341 aatgagtatg caaactgaaa ttgagtcaat tagagagata aatgacattg ctaaacagtt
     5401 aaatcaaaaa catcaaatta tgttaatgat tgattggaag gatagacgtg aaggggttat
     5461 aacttatgat gtactaaatt atattgaaga aatcatcaaa atgactcata ttcaattaat
     5521 aggtattgca tttaacttta tgtgtttcaa gtcttcggct ccgactgaag aagatatatt
     5581 aaagataaat caattcgttg atgctattga atataattta ggatttagac taaaagttgt
     5641 atcaggagga aactcaagta tgatacccca attaatgtac aatgatttgg gtaggattaa
     5701 tgagttacga ataggtgagg cattatttag agggatagat actacaacaa atcaatctat
     5761 acccatgcta tttcagaatg caattacagt agaagcggaa attttagaga ttaaaccacg
     5821 tctatctgac aataatcaat gctatttaca agcaattgta gatattggct atgttgacac
     5881 agacgtaaat aaaattaaac ctattaagaa tgatgttagc attgttggtg catcaagtga
     5941 tcatctaatg attaatttaa ataatcaaga ttactataaa gttggtgata ttatagaatt
     6001 tgctatggag tatgaggcgc tttctcaagt aatgtatcat aaccatatga caaagcacta
     6061 ttttaaggat aattatattc aatctttgaa tagtatgatg gtcgattctc cattattgat
     6121 taataaaaaa tgttaaccaa ttctttgtag gtattaatta tcatataaac tttaataaat
     6181 taattagcct ttaattttga attcattctg attaatggct ttttatttta tcatttaaag
     6241 gtaaaatcca ttaataatta aaattctaat ttacttttat aaaaaaatta aaaaatacac
     6301 caaattatat tgacattgat aatcgttatc aataaactat gtattgtaaa cctatacata
     6361 ttgaggagtg gaattcatga aaggctttaa gtttgcaggt atagtcgcat tattatttgc
     6421 attagtttta gttactgctt gtggtaatgt tagcaataat ggatcaggtg attcaggtaa
     6481 taaatcgtca tcgaaagatt ctattaaaat taaacacgaa ttaggcacaa ctaaagttcc
     6541 taaagatgct aaacgtgtcg tagcgttgga attttcattt gtagatgctt tagcggcact
     6601 aaatgttaaa cctgttgggg ttgctgatga caacaaacca aatcgtatta ttaaaccatt
     6661 aaaagaaaaa attggagatt ataaatctgt tggtgctcgt aaacaaccca acttagaaga
     6721 aatcagtaaa ttaaaaccag atttaattat tgcagatagt aacagacaca aaggtattta
     6781 caaagaatta agtaaaattg ctccaacaat tgaattaaaa agttttgatg gagattataa
     6841 tgataatata gatgctttta aaacaattgc caaagcttta aataaagaag atgaaggtaa
     6901 gaaacgttta gacgagcata aagagaagat tgcaaaatat aaagatgaaa ttcaatttga
     6961 taaaaatgaa aaggtattac cagctgtagc gtctaaatct ggcttattag cacatccaag
     7021 tgaatcttat gtaggtcaat tcttaagtca acttggcttt aaagaagcat taaataaaga
     7081 tgtcactaaa gggttaagca aatatttaca aggaccttat ttacaactta atgcagaaac
     7141 attaaaagac gtaaatcctg aacgtatgtt tataatgact gatggcgcaa gtcctaaaga
     7201 accatcatat caagaaatga aaaaagaccc ggtttgggac acattagatg cggttaaaca
     7261 taatcgtgta agtatcgtta gtcgtgatac ttgggcaaga gctcgaggtt taatatcttc
     7321 tgaagaaatg gctaaagaac ttgtagaaat ttctaaaaaa gataaagaaa agtaaggtgg
     7381 caataaaatg actattagat ctactgatag tcaatctgct ttagacaaag caaataagag
     7441 gcgcactaca ctcacattta ttgtgagtgg gtgctttctt tttatttttg catattttaa
     7501 tttagcgatt ggctcgtctg aaattcatgc taaacatatt tttgaatact tttttacatc
     7561 tataaataat aaacaaacat ttcttattca taatgtaaga atgccaagaa tgattggtgg
     7621 gttattgatt ggcggtgcgc tagccttagc tggcctctta atgcaagcga ttactaggaa
     7681 tccattagca tctccacaaa tatttggtgt taattcaggt gcatcatttg taatagtatt
     7741 agtgacgata ttaatacctt cactaggtaa ctatgcaaca tatctggcat ttttaggggc
     7801 atttattgga ggattaactg tctatgtatt atccggatct acgaaaaaaa taacaccaat
     7861 taaattggcc cttgcaggaa tggcaattca tttatttttc agtagtttaa cgcaaggtat
     7921 catcatttta aatgaagatt ctaatactac cgttatgttc tggttagtag gttcattaaa
     7981 tggattgaaa tggactgcag tcttgtcagt tatgcctttg ctcatattag cgcttatcat
     8041 aacgatgtta ttaggccgtc aattaaccat aatggaatta ggagacgata tagcgaaagg
     8101 attaggccag aagactcagc ttatcagaat tatagttggc ctacttgtca tcgtactagc
     8161 aggtgcatct gtttcaatag ttggaccgat tggattcatt ggtttaatcg tccctcatat
     8221 agttaaacgt tatataagta aagattactt cttaatggtg cctttaactt ttttgatagg
     8281 tgccgattta ttattactat cagatatgtt aagtagactt attacatttc cttacgaatc
     8341 tccagttggt attgtcactt catttgttgg ggcaatttac ttcctattaa taactttaaa
     8401 aggggtgaaa cgaatatgac aaaacgacaa ttatctattc gttacactgt tgtaatcatc
     8461 tgcttaattg taagcatatt tataagttta tgtgttggtt caacaatgta cagtcctttg
     8521 aaagcaattc acggaattct aaaatttgat gatttcatat taaacgagta ccgaattccg
     8581 agaacgttac taggtttagt tgtgggaagt agtttggcca tttctggcgc ggtgattcaa
     8641 ggggtagtta gaaatccact agcatctcca gatgttatag gtataactaa aggcgctagt
     8701 ttggcagcta ttatagtaat tatgctattt ccttcagcgc cgctattagt actacccatt
     8761 ggttcgttca taggtgcatt atttattagt ttgattttgt catttttaat ttctaaatat
     8821 aatattaaag gctcaacttt agctttaatt gggttagcta tcggtgctat atgtaccgct
     8881 gtagttcaat ttttacttat tagaaaccct atggatgcaa ataatgcgtt agtttggtta
     8941 acagggagtt tatatggtca tactattgaa aatttctatt cagtcatacc ctggtttgtt
     9001 ataaccttac cactcgtatt atgtttaagt tatcaattag atattttaaa tttaggagaa
     9061 catattgcta cggcgcttgg tgcaagagta caaagactca aaatgatctt acttattttg
     9121 tcggttatgc tggctggtgc ctccatttca gtagtaggcg gtataagttt tctaggccta
     9181 attgcaccac atatcgctag atctattgta ggtttacgtt acttccatgt tgtaattatg
     9241 tctggttgta taggttcaat tttaatcttg ttcagtgatg ggttagcgag aggaattcat
     9301 ccaccattag atatacctgt gggtgtaata attgctatca ttggggtgcc atatttctta
     9361 tttttattaa gacgaattta atgaaattca agagctaatt attctcatat ttatgatgaa
     9421 aattagctct ttttatattg catatcaatt aaaaatgata tatagtattt aacatgatat
     9481 ttataaaaat gcatatattc ttatatttat ataaaagttc acagttttac ttaatatatt
     9541 tacataatca atgaatataa aagcatcaat aatgagaaag aaagaggtta ttagtggtgg
     9601 aaggttactc aaagcaacag attgccaaag gtagagcgaa attcataact atgtctatta
     9661 ttggaattat acttttctta attccagtac cagttacaca agatggtgag aaacaaacta
     9721 cattacctgt agccttttta gcaaattggc taaaaggtct actaggtgat gcaatgccaa
     9781 ttattataat ttttattatt acattgtctg caatattaac agtactttat tcgacaattt
     9841 ttaaaagtaa agttaaacta ggcggattat tagatagtgc atttaaagtt ggtccagtat
     9901 ggatgacatt aagaatatta gccgtcgtct ttgtatggat gacctatttt aaacttggtt
     9961 caaaggttat ttattcagag gatactggtg gtttagtgtt ttatgatctt ttacctacat
    10021 tggttgcagt atttttattt gctgcactat tcttaccttt tttaatgg
//
